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Isobutyric anhydride is used in the preparation of 4-O-isobutyryl derivative by reacting with octyl beta-D-glucopyranoside using C2-symmetric chiral 4-pyrrolidinopyridine as a catalyst. It acts as a starting material for esters like sucrose acetate isobutyrate, dyes and agrochemicals. It finds application as fragrance intermediate and flavorings.
Lamers, P.; Priebbenow, D. L.; Bolm, C. Iron-Catalyzed Acylative Dealkylation of N-Alkylsulfoximines. Eur. J. Org. Chem. 2015, 2015 (25), 5594-5602.
Qi, X.; Jiang, L. B.; Li, C. L.; Li, R.; Wu, X. F. Palladium-Catalyzed One-Pot Carbonylative Sonogashira Reaction Employing Formic acid as the CO Source. Chem. Asian J. 2015, 10 (9), 1870-1873.
Hazard Statements: H227-H311-H314-H331
Combustible liquid. Toxic in contact with skin. Causes severe skin burns and eye damage. Toxic if inhaled.
Precautionary Statements: P210-P233-P240-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P311-P363-P374-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Fight fire with normal precautions from a reasonable distance. Dispose of contents/ container to an approved waste disposal plant