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Isobutyric anhydride is used in the preparation of 4-O-isobutyryl derivative by reacting with octyl beta-D-glucopyranoside using C2-symmetric chiral 4-pyrrolidinopyridine as a catalyst. It acts as a starting material for esters like sucrose acetate isobutyrate, dyes and agrochemicals. It finds application as fragrance intermediate and flavorings.
Lamers, P.; Priebbenow, D. L.; Bolm, C. Iron-Catalyzed Acylative Dealkylation of N-Alkylsulfoximines. Eur. J. Org. Chem. 2015, 2015 (25), 5594-5602.
Qi, X.; Jiang, L. B.; Li, C. L.; Li, R.; Wu, X. F. Palladium-Catalyzed One-Pot Carbonylative Sonogashira Reaction Employing Formic acid as the CO Source. Chem. Asian J. 2015, 10 (9), 1870-1873.
Hazard Statements: H227-H302-H312-H314-H318
Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210u-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.