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79099-07-3 - 1-Boc-4-piperidone, 99% - 1-(tert-Butoxycarbonyl)-4-piperidone - tert-Butyl 4-oxo-1-piperidinecarboxylate - L13361 - Alfa Aesar

L13361 1-Boc-4-piperidone, 99%

CAS Number
79099-07-3
Synonyms
1-(tert-Butoxycarbonyl)-4-piperidone
tert-Butyl 4-oxo-1-piperidinecarboxylate

Size Price ($) Quantity Availability
10g 71.80
50g 271.00
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1-Boc-4-piperidone, 99%

MDL
MFCD00151800

Chemical Properties

Formula
C10H17NO3
Formula Weight
199.25
Melting point
72-76°
Solubility
Soluble in methanol. Slightly soluble in water.

Applications

1-Boc-4-piperidone is used as a pharmaceutical intermediate. It is involved in the preparation of 1-piperidin-4-yl-substituted butyro- and valerolactams.

Notes

Incompatible with strong oxidizing agents and metals.

Literature References

Yamashita, H.; Demizu, Y.; Misawa, T.; Shoda, T.; Kurihara, M. Synthesis of a bis-cationic alpha,alpha-disubstituted amino acid (9-amino-bispidine-9-carboxylic acid) and its effects on the conformational properties of peptides. Tetrahedron 2015, 71 (15), 2241-2245.

Park, J. H.; Lee, G. E.; Lee, S. D.; Hien, T. T.; Kim, S.; Yang, J. W.; Cho, J. H.; Ko, H.; Lim, S. C.; Kim, Y. G.; Kang, K. W.; Kim, Y. C. Discovery of Novel 2,5-Dioxoimidazolidine-Based P2X7 Receptor Antagonists as Constrained Analogues of KN62. J. Med. Chem. 2015, 58 (5), 2114-2134.

Other References

Beilstein
3650236
Harmonized Tariff Code
2933.39
TSCA
No

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