Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

L13361 1-Boc-4-piperidone, 99%

CAS Number
79099-07-3
Synonyms
1-(tert-Butoxycarbonyl)-4-piperidone
tert-Butyl 4-oxo-1-piperidinecarboxylate

Stock No. Size Price ($) Quantity Availability
L13361-09 10g 65.10
L13361-18 50g 245.00
Add to Cart Bulk/Specialty Print Quote View Item

1-Boc-4-piperidone, 99%

MDL
MFCD00151800

Chemical Properties

Formula
C10H17NO3
Formula Weight
199.25
Melting point
72-76°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in methanol. Slightly soluble in water.

Applications

1-Boc-4-piperidone is used as a pharmaceutical intermediate. It is involved in the preparation of 1-piperidin-4-yl-substituted butyro- and valerolactams.

Notes

Incompatible with strong oxidizing agents and metals.

Literature References

Yamashita, H.; Demizu, Y.; Misawa, T.; Shoda, T.; Kurihara, M. Synthesis of a bis-cationic alpha,alpha-disubstituted amino acid (9-amino-bispidine-9-carboxylic acid) and its effects on the conformational properties of peptides. Tetrahedron 2015, 71 (15), 2241-2245.

Park, J. H.; Lee, G. E.; Lee, S. D.; Hien, T. T.; Kim, S.; Yang, J. W.; Cho, J. H.; Ko, H.; Lim, S. C.; Kim, Y. G.; Kang, K. W.; Kim, Y. C. Discovery of Novel 2,5-Dioxoimidazolidine-Based P2X7 Receptor Antagonists as Constrained Analogues of KN62. J. Med. Chem. 2015, 58 (5), 2114-2134.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3650236
Harmonized Tariff Code
2933.39
TSCA
No

Recommended

  • A10124

    alpha-Toluenesulfonyl chloride, 99%
  • A10559

    Iodomethane, 99%, stab. with copper
  • A10832

    2-Chlorobenzoic acid, 98+%
  • A11596

    Phenyl isothiocyanate, 97%
  • A12534

    (1-Pentyl)triphenylphosphonium bromide, 98%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware