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125700-67-6 - O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99% - TBTU - L13470 - Alfa Aesar

L13470 O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%

CAS Number
125700-67-6
Synonyms
TBTU

Size Price ($) Quantity Availability
1g 15.04
5g 43.36
25g 140.08
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O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%

MDL
MFCD00077413
EINECS
423-040-4

Chemical Properties

Formula
C11H16BF4N5O
Formula Weight
321.08
Melting point
195-198° dec.
Solubility
Soluble in acetonitrile (100 mg/ml, clear, colorless), DMF (160.55 mg/ml, clear), and water (3 mg/ml at 20°C).

Applications

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate is used as used for solid-phase peptide synthesis. It is also used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides.

Notes

Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2-8°C. Sensitive to light and moisture. Store under inert gas.

Literature References

Iman Abdelmoty.; Fernando Albericio.; Louis A. Carpino.; Bruce M. Foxman.; Steven A. Kates. Structural studies of reagents for peptide bond formation: Crystal and molecular structures of HBTU and HATU. Letters in Peptide Science. 1986, 94 (1), 57-67.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
7066325
Harmonized Tariff Code
2933.99
TSCA
No

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