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L13883 Imidazole-2-carboxaldehyde, 97%

CAS Number
10111-08-7
Synonyms
2-Formylimidazole

Stock No. Size Price ($) Quantity Availability
L13883-06 5g 84.90
L13883-14 25g 310.00
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Imidazole-2-carboxaldehyde, 97%

MDL
MFCD00003544
EINECS
000-000-0

Chemical Properties

Formula
C4H4N2O
Formula Weight
96.09
Melting point
ca 205° dec.
Storage & Sensitivity
Keep Cold. Air Sensitive.
Solubility
Soluble in water.

Applications

Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines.

Notes

Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literature References

Joseyphus, R. S.; Shiju, C.; Joseph, J.; Dhanaraj, C. J.; Arish, D. Synthesis and characterization of metal complexes of Schiff base ligand derived from imidazole-2-carboxaldehyde and 4-aminoantipyrine. Spectrochim. Acta, Part A 2014, 133, 149-155.

Tinel, L.; Dumas, S.; George, C. A time-resolved study of the multiphase chemistry of excited carbonyls: Imidazole-2-carboxaldehyde and halides. C. R. Chim. 2014, 17 (7), 801-807.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
4371302
Harmonized Tariff Code
2912.49
TSCA
No

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