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Dowex® 50WX4 200-400 (H) is used to investigate the effect of particle size on drug loading and release profiles. Dowex® 50WX4 hydrogen form when treated in boiling water converted D,L-glyceraldehyde 3-phosphate diethyl acetal (barium salt) to free aldehyde D,L-glyceraldehyde 3-phosphate. It is a useful column packing material, used in anion exchange chromatography.
Seong Hoon Jeong.; Kinam Park. Drug loading and release properties of ion-exchange resin complexes as a drug delivery matrix. International Journal of Pharmaceutics. 2008, 361 (1), 26-32.
Maybelle K Go.; Tina L Amyes.; John P Richard. Hydron transfer catalyzed by triosephosphate isomerase. Products of the direct and phosphite-activated isomerization of [1-(13)C]-glycolaldehyde in D(2)O. Biochemistry (Washington). 2009, 48 (24), 5769-5778.
Strongly acidic cation-exchange resin, 4% cross-linked, H+ form, 200-400 mesh (dry).
Hazard Statements: H318
Causes serious eye damage.
Precautionary Statements: P280-P305+P351+P338-P310
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.