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N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.
S Narayanan. Sialic acid as a tumor marker. Annals of Clinical & Laboratory Science. 1994, 24, (4), 376-384.
M. Mahmoudian; D. Noble; C.S. Drake; R.F. Middleton; D.S. Montgomery; J.E. Piercey; D. Ramlakhan; M. Todd; M.J. Dawson. An efficient process for production of n-acetylneuraminic acid using n-acetylneuraminic acid aldolase. Enzyme and Microbial Technology. 1997, 20, (5), 393-400.