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Benzyl (R)-(-)-glycidyl ether is used in the preparation of the lactone fragment of compactin and mevinolin. Chiron in the preparation of syn-1,3-polyols, dideoxynucleosides, and a spiroacetal cyanohydrin.
E Abushanab; M S Sarma. 1',2'-seco-dideoxynucleosides as potential anti-HIV agents. Journal of Medicinal Chemistry. 1989, 32, (1), 76-79.
Fatih M. Uckun; Chen Mao, Alexei O. Vassilev; He Huang; Shyi-Tai Jan. Structure-based design of a novel synthetic spiroketal pyran as a pharmacophore for the marine natural product spongistatin 1. Bioorganic & Medicinal Chemistry Letters. 2000, 10, (6), 541-545.
Hazard Statements: H315-H319-H341
Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects.
Precautionary Statements: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.