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14618-80-5 - Benzyl (R)-(-)-glycidyl ether, 98+% - (R)-(-)-2-(Benzyloxymethyl)oxirane - L13980 - Alfa Aesar

L13980 Benzyl (R)-(-)-glycidyl ether, 98+%

CAS Number
14618-80-5
Synonyms
(R)-(-)-2-(Benzyloxymethyl)oxirane

Size Price ($) Quantity Availability
1g 60.93
5g 255.44
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Benzyl (R)-(-)-glycidyl ether, 98+%

MDL
MFCD00068409

Chemical Properties

Formula
C10H12O2
Formula Weight
164.20
Boiling Point
130°/0.1mm
Flash Point
>110°(230°F)
Density
1.072
Refractive Index
1.5170
Solubility
Soluble in water.

Applications

Benzyl (R)-(-)-glycidyl ether is used in the preparation of the lactone fragment of compactin and mevinolin. Chiron in the preparation of syn-1,3-polyols, dideoxynucleosides, and a spiroacetal cyanohydrin.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.

Literature References

E Abushanab; M S Sarma. 1',2'-seco-dideoxynucleosides as potential anti-HIV agents. Journal of Medicinal Chemistry. 1989, 32, (1), 76-79.

Fatih M. Uckun; Chen Mao, Alexei O. Vassilev; He Huang; Shyi-Tai Jan. Structure-based design of a novel synthetic spiroketal pyran as a pharmacophore for the marine natural product spongistatin 1. Bioorganic & Medicinal Chemistry Letters. 2000, 10, (6), 541-545.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H315-H319

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P201-P280-P281-P305+P351+P338-P362-P308+P313-P321-P332+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). If skin irritation occurs: Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3588399
Harmonized Tariff Code
2910.90
TSCA
No
RTECS
TX2860030

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