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4767-03-7 - 2,2-Bis(hydroxymethyl)propionic acid, 98+% - L14014 - Alfa Aesar

L14014 2,2-Bis(hydroxymethyl)propionic acid, 98+%

CAS Number
4767-03-7
Synonyms

Size Price ($) Quantity Availability
100g 27.80
500g 67.40
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2,2-Bis(hydroxymethyl)propionic acid, 98+%

MDL
MFCD00004199
EINECS
225-306-3

Chemical Properties

Formula
C5H10O4
Formula Weight
134.13
Melting point
187-191°
Sensitivity
Hygroscopic
Solubility
Soluble in acetone (slightly), methanol, and water. Insoluble in benzene.

Applications

2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the “click” azide-acetylene cycloaddition.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature.

Literature References

Elizabeth R. Gillies.; Jean M.J. Fréchet. Dendrimers and dendritic polymers in drug delivery. Drug Discovery Today. 2005, 10 (1), 35-43.

Ihre H.; Hult A. Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid. Macromolecules. 1999, 31 (13), 4061-4068.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3253
Beilstein
1756385
Harmonized Tariff Code
2918.19
TSCA
Yes

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