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2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the click azide-acetylene cycloaddition.
Elizabeth R. Gillies.; Jean M.J. Fréchet. Dendrimers and dendritic polymers in drug delivery. Drug Discovery Today. 2005, 10 (1), 35-43.
Ihre H.; Hult A. Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid. Macromolecules. 1999, 31 (13), 4061-4068.
Hazard Statements: H319-H335
Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280i-P304+P340-P305+P351+P338-P312-P337+P313-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant