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L14014 2,2-Bis(hydroxymethyl)propionic acid, 98+%

CAS Number
4767-03-7
Synonyms

Stock No. Size Price ($) Quantity Availability
L14014-22 100g 29.20
L14014-36 500g 70.80
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2,2-Bis(hydroxymethyl)propionic acid, 98+%

MDL
MFCD00004199
EINECS
225-306-3

Chemical Properties

Formula
C5H10O4
Formula Weight
134.13
Melting point
187-191°
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Solubility
Soluble in acetone (slightly), methanol, and water. Insoluble in benzene.

Applications

2,2-Bis(hydroxymethyl)propionic acid is used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy Simple derivatives of this acid have been used to construct dendritic architectures via the “click” azide-acetylene cycloaddition.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is hygroscopic in nature.

Literature References

Elizabeth R. Gillies.; Jean M.J. Fréchet. Dendrimers and dendritic polymers in drug delivery. Drug Discovery Today. 2005, 10 (1), 35-43.

Ihre H.; Hult A. Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid. Macromolecules. 1999, 31 (13), 4061-4068.

GHS Hazard and Precautionary Statements

Hazard Statements: H319-H335

Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280i-P304+P340-P305+P351+P338-P312-P337+P313-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3253
Beilstein
1756385
Harmonized Tariff Code
2918.19
TSCA
Yes

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