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Ethyl hexafluoroglutaryl chloride is used as a derivatising agent in gas chromatography. It is an active reagent used for the quantization of amphetamine and methamphetamine in urine by gas chromatography/mass spectroscopy (GC/MS).
Pace, A.; Buscemi, S.; Vivona, N. The synthesis of fluorinated heteroaromatic compounds. Part 1. Five-membered rings with more than two heteroatoms. Org. Prep. Proc. Int. 2005, 37 (5), 447-506.
Prakash, G. S.; Hu, J.; Olah, G. A. Alkylation of in situ generated fluorinated alkoxides: novel synthesis of partially fluorinated ethers. Arkivoc 2003, 3, 104-119.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.