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L14186 3',4',5,7-Tetrahydroxyflavone, 97%

CAS Number
491-70-3
Synonyms
Luteolin

Stock No. Size Price ($) Quantity Availability
L14186-MC 100mg 64.20
L14186-ME 500mg 225.00
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3',4',5,7-Tetrahydroxyflavone, 97%

MDL
MFCD00017309
EINECS
207-741-0

Chemical Properties

Formula
C15H10O6
Formula Weight
286.24
Melting point
>300°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), dimethyl sulfoxide (7 mg/ml), 1eq. Sodium hydroxide (5 mM), dimethylformamide (~20 mg/ml), water (1 mg/ml) at 25°C and methanol.

Applications

3',4',5,7-Tetrahydroxyflavone is used as an apoptosis inducer.

Notes

Incompatible with strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2 - 8°C.

Literature References

NK Peters.; JW Frost.; SR Long. A plant flavone, luteolin, induces expression of Rhizobium meliloti nodulation genes. Science. 1986, 233 (4767), 977-980.

Seelinger G.; Merfort I.; Schempp CM. Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin. Planta Medica. 2007, 208 (15), 1694-1706.

Anti-oxidant and radical scavenger in biological systems: Methods Enzymol., 234, 420 (1994).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,5614
Beilstein
292084
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
LK9275210

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