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942-24-5 - Methyl indole-3-carboxylate, 99% - Indole-3-carboxylic acid methyl ester - L14516 - Alfa Aesar

L14516 Methyl indole-3-carboxylate, 99%

CAS Number
942-24-5
Synonyms
Indole-3-carboxylic acid methyl ester

Size Price ($) Quantity Availability
25g 35.28
100g 131.40
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Methyl indole-3-carboxylate, 99%

MDL
MFCD00189407

Chemical Properties

Formula
C10H9NO2
Formula Weight
175.19
Melting point
149-152°
Solubility
Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.

Applications

Reactant used for preparation of nitric oxide synthesis (nNOS) inhibitors, protein kinase c alpha (PKCα) inhibitors, inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents, kinase insert domain receptor (KDR) inhibitors, organocatalysts for the anti-Mannich reaction, very late antigen-4 (VLA-4) antagonists, inhibitors of Human 5-Lipoxygenase, serotonin 5-HT4 receptor antagonists and hyaluronidase inhibitors.

Notes

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Jane F. Djung et. al. The synthesis and evaluation of indolylureas as PKCα inhibitors. Bioorganic & Medicinal Chemistry2011, 19(8), 2742-2750.

Takahiro Honda et. al. KDR inhibitor with the intramolecular non-bonded interaction: Conformation-activity relationships of novel indole-3-carboxamide derivatives. Bioorganic & Medicinal Chemistry Letters,. 2011, 21 (6), 1782-1785.

Other References

Beilstein
142023
Harmonized Tariff Code
2933.99
TSCA
No

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