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961-07-9 - 2'-Deoxyguanosine hydrate, 99% - 9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate - Guanine-2'-deoxyriboside hydrate - L14519 - Alfa Aesar

L14519 2'-Deoxyguanosine hydrate, 99%

CAS Number
961-07-9
Synonyms
9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate
Guanine-2'-deoxyriboside hydrate

Size Price ($) Quantity Availability
100mg 39.24
500mg 110.60
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2'-Deoxyguanosine hydrate, 99%

MDL
MFCD00150760
EINECS
213-505-8

Chemical Properties

Formula
C10H13N5O4•xH2O
Formula Weight
267.25(anhy)
Solubility
Slightly soluble in water.

Applications

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Notes

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Kasper Broedbaek; Allan Weimann; Elisabeth S. Stovgaard; Henrik E. Poulsen. Urinary 8-oxo-7,8-dihydro-2?-deoxyguanosine as a biomarker in type 2 diabetes. Free Radical Biology and Medicine2011, 51(8), 1473-1479.

Aaron M Fleming; Arunkumar Kannan; James G Muller; Yi Liao; Cynthia J Burrows. Copper/H2O2-mediated oxidation of 2'-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts. Journal of Organic Chemistry,2011, 76 (19), 7953-7963.

Other References

Beilstein
39814
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
MF8760000

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