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Chloroform is a commonly used laboratory solvent. It was previously used as an anesthetic. It is also used as a precursor to PTFE and refrigerants. Chloroform was used in the past as an extraction solvent for fats, oils and greases. It is useful for the rapid and simple release of periplasmic proteins. The mixture of guanidinium thiocyanate-phenol-chloroform, plays an essential role in the RNA isolation process.
Fong, J. K.; Pena, J. K.; Xue, Z.; Alam, M. M.; Sampathkumaran, U.; Goswani, K. Optical Sensors for the Detection of Trace Chloroform. Anal. Chem. 2015, 87 (3), 1569-1574.
Yadav, R.; Balasubramanian, K.; Wang, X. Encapsulation of gold nanoparticles with PHB based on coffee ring effect. RSC Adv. 2015, 5 (24), 18501-18505.
Hazard Statements: H302-H331-H315-H319-H351-H361-H372
Harmful if swallowed. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Causes damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P201-P280-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.