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Chloroform is a commonly used laboratory solvent. It was previously used as an anesthetic. It is also used as a precursor to PTFE and refrigerants. Chloroform was used in the past as an extraction solvent for fats, oils and greases. It is useful for the rapid and simple release of periplasmic proteins. The mixture of guanidinium thiocyanate-phenol-chloroform, plays an essential role in the RNA isolation process.
Fong, J. K.; Pena, J. K.; Xue, Z.; Alam, M. M.; Sampathkumaran, U.; Goswani, K. Optical Sensors for the Detection of Trace Chloroform. Anal. Chem. 2015, 87 (3), 1569-1574.
Yadav, R.; Balasubramanian, K.; Wang, X. Encapsulation of gold nanoparticles with PHB based on coffee ring effect. RSC Adv. 2015, 5 (24), 18501-18505.
Hazard Statements: H302-H315-H319-H331-H335-H336-H351-H361d-H373
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Toxic if inhaled. May cause respiratory irritation. May cause drowsiness or dizziness. Suspected of causing cancer. Suspected of damaging the unborn child. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If skin irritation occurs: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant