L15193 3-(Hydroxymethyl)benzeneboronic acid, 98%
SDS
| Stock No. | Size | Price ($) | Quantity | Availability |
|---|---|---|---|---|
| L15193-03 | 1g | 45.60 |
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| L15193-06 | 5g | 121.00 |
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3-(Hydroxymethyl)benzeneboronic acid, 98%
Chemical Properties
Applications
Reactant used for copper-mediated trifluoromethylation, copper-catalyzed transformations from arylboronic acids in water, Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate. Reactant involved in the synthesis of biologically active molecules including Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions, HIV protease inhibitors with antiviral activity against drug-resistant viruses, Pyrrole derivatives for use as PDE4B inhibitors.
Notes
Literature References
Cheng-Pan Zhang et. al. Copper-mediated trifluoromethylation of arylboronic acids by trifluoromethyl sulfonium salts.. ChemicalCommunications.2011, 47,(33), 9516-9518.
Haijun Yang et. al. General copper-catalyzed transformations of functional groups from arylboronic acids in water. Chemistry: A European Journal.2011, 17, (20), 5652-5660.
GHS Hazard and Precautionary Statements
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant
