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4,4'-Methylenebis(phenyl isocyanate) acts as a monomer in the production of polyurethane. The rigid polyurethane foams are good thermal insulators, which find applications in all freezers and refrigerators, as well as in buildings. It is also used as an industrial strength adhesive, which is available to end consumers as various high-strength bottled glue preparations.
Chong, D. S. T.; Turner, L. A.; Gadegaard, N.; Seifalian, A. M.; Dalby, M. J.; Hamilton, G. Nanotopography and Plasma Treatment: Redesigning the Surface for Vascular Graft Endothelialisation. Eur. J. Vasc. Endovasc. 2015, 49 (3), 335-343.
Hazard Statements: H315-H317-H319-H332-H334-H335-H351-H373
Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. Harmful if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Suspected of causing cancer. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P201-P202-P260-P264b-P271-P272-P280-P281-P285-P302+P352-P304+P340-P305+P351+P338-P308+P313-P333+P313-P337+P313-P342+P311-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation or rash occurs: If eye irritation persists: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant