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5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-α,β-D-ribofuranose is used as a starting material for the preparation of N-benzyl alfa-L-manno aminocyclopentitol , 4-deoxy-N-benzyl-alfa-L-manno aminocyclopentitol and N-benzyl 6,7-di-epi-trehalamine using stereoselective allylation. It is also used in oligosaccharides.
Ceballos, C.; Prata, C. A. H.; Giorgio, S.; Garzino, F.; Payet, D.; Barthélémy, P.; Grinstaff, M. W.; Camplo, M. Cationic Nucleoside Lipids Based on a 3-Nitropyrrole Universal Base for siRNA Delivery. Bioconjugate Chem. 2009, 20 (2), 193-196.
Suydam, I. T.; Strobel, S. A. Fluorine Substituted Adenosines As Probes of Nucleobase Protonation in Functional RNAs. J. Am. Chem. Soc. 2008, 130 (41), 13639-13648.