Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

7782-89-0 - Lithium amide, 95% - Lithamide - L16023 - Alfa Aesar

L16023 Lithium amide, 95%

CAS Number
7782-89-0
Synonyms
Lithamide

Size Price ($) Quantity Availability
25g 26.20
100g 52.30
500g 198.00
Add to Cart Add to Quote Request View Item

Lithium amide, 95%

MDL
MFCD00011093
EINECS
231-968-4

Chemical Properties

Formula
H2LiN
Formula Weight
22.96
Melting point
373°
Boiling Point
430°
Density
1.178
Sensitivity
Air & Moisture Sensitive
Solubility
Slightly soluble in ethanol and liquid ammonia. Insoluble in anhydrous ether, benzene and toluene.

Applications

Lithium amide is used in the preparation of active pharmaceutical ingredients and antioxidants. It acts as a catalyst for polymers, as nucleophiles and as strong bases. It serves as a reagent in the synthesis of antiinflamatory and preoresolving protectin D1, chemotype dipeptidyl peptidase IV inhibitors and sterically congested triarylamines. It finds application in dyes displaying large stokes shifts. In addition to this, it is used as a reagent for cross-coupling of aryl chlorides and amine.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents, acids, water and alcohols.

Literature References

Sasaki, M.; Kondo, Y.; Moto-ishi, T. I.; Kawahata, M.; Yamaguchi, K.; Takeda, K. Enantioselective Synthesis of Allenylenol Silyl Ethers via Chiral Lithium Amide Mediated Reduction of Ynenoyl Silanes and Their Diels-Alder Reactions. Org. Lett. 2015, 17 (5), 1280-1283.

Lesage, D.; Barozzino-Consiglio, G.; Duwald, R.; Fressigné, C.; Harrison-Marchand, A.; Faull, K. F.; Maddaluno, J.; Gimbert, Y. A Lithium Amide Protected Against Protonation in the Gas Phase: Unexpected Effect of LiCl. J. Org. Chem. 2015, 80 (12), 6441-6446.

GHS Hazard and Precautionary Statements

Hazard Statements: H261-H314-H318

In contact with water releases flammable gas. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P280-P305+P351+P338-P309-P310-P370+P378m-P402

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. In case of fire: Use for extinction: Limestone powder. Store in a dry place.

Other References

Merck
14,5522
Hazard Class
4.3
Packing Group
II
Harmonized Tariff Code
2853.00
TSCA
Yes
RTECS
OJ5590000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware