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Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mTORC2). Further, it serves as a reagent in the synthesis of O-aryl N-isopropylcarbamates. In addition to this, it is used as a derivatization reagent during the stereoisomeric analysis of secondary alcohols.
Otto, A.; Grube, T.; Schiebahn, S.; Stolten, D. Closing the loop: captured CO2 as a feedstock in the chemical industry. Energy Environ. Sci. 2015, 8 (11), 3283-3297.
Zou, L.; Wang, X. Y.; Zhang, X. X.; Dai, Y. Z.; Wu, Y. D.; Wang, J. Y.; Pei, J. Toward electron-deficient pyrene derivatives: construction of pyrene tetracarboxylic diimide containing five-membered imide rings. Chem. Commun. 2015, 51 (63), 12585-12588.
Hazard Statements: H225-H330-H315-H319-H334-H335
Highly flammable liquid and vapour. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.