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5-Fluorocytosine acts as an antidiabetic, antifungal and antimicrobial agent. It is useful for the treatment of serious infections arises due to susceptible strains of Candida or Cryptococcus neoformans and chromomycosis. Further, it is employed in studies on TMP biosynthesis.
Olszewska, A.; Dadová, J.; Mačková, M.; Hocek, M. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg. Med. Chem. 2015, 23 (21), 6885-6890.
Perumalla, S. R.; Sun, C. C. Enabling Tablet Product Development of 5-Fluorocytosine Through Integrated Crystal and Particle Engineering. J. Pharm. Sci. 2014, 103 (4), 1126-1132.