Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

50-91-9 - 5-Fluoro-2'-deoxyuridine, 98+% - 2'-Deoxy-5-fluorouridine - Floxuridine - L16497 - Alfa Aesar

L16497 5-Fluoro-2'-deoxyuridine, 98+%

CAS Number
50-91-9
Synonyms
2'-Deoxy-5-fluorouridine
Floxuridine

Size Price ($) Quantity Availability
100mg 80.00
500mg 264.00
Add to Cart Add to Quote Request View Item

5-Fluoro-2'-deoxyuridine, 98+%

MDL
MFCD00006530
EINECS
200-072-5

Chemical Properties

Formula
C9H11FN2O5
Formula Weight
246.20
Melting point
148-151°
Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Applications

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

Notes

Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Literature References

Rooney, J. P.; Luz, A. L.; Gonzalez-Hunt, C. P.; Bodhicharla, R.; Ryde, I. T.; Anbalagan, C.; Meyer, J. N. Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. Exp. Gerontol. 2014, 56, 69-76.

Kruspe, S.; Hahn, U. An Aptamer Intrinsically Comprising 5-Fluoro-2'-deoxyuridine for Targeted Chemotherapy. Mol. BioSyst. 2014, 53 (39), 10541-10544.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H341-H360

Harmful if swallowed. Suspected of causing genetic defects. May damage fertility or the unborn child.

Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4112
Beilstein
2645818
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
YU7535000

Recommended

  • A10926

    Diethylenetriaminepentaacetic acid, 98+%
  • A11079

    Sodium butyrate, 98+%
  • A12075

    Cacodylic acid, 98%
  • 11287

    Gadolinium(III) chloride hexahydrate, REacton®, 99.99% (REO)
  • 14248

    Iodine, crystalline, 99.5%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware