Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

67442-07-3 - 2-Chloro-N-methoxy-N-methylacetamide, 98% - L17048 - Alfa Aesar

L17048 2-Chloro-N-methoxy-N-methylacetamide, 98%

CAS Number
67442-07-3
Synonyms

Size Price ($) Quantity Availability
5g 66.23
25g 211.15
Add to Cart Add to Quote Request View Item

2-Chloro-N-methoxy-N-methylacetamide, 98%

MDL
MFCD00134232

Chemical Properties

Formula
C4H8ClNO2
Formula Weight
137.57
Melting point
39-41°
Boiling Point
94-95°/9mm
Flash Point
104°(219°F)
Solubility
Insoluble in water.

Applications

2-Chloro-N-methoxy-N-methylacetamide is used in the preparation of 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS) and structurally related 2-alkyl-4-quinolones having biological activity, 2-(benzo[d]thiazol-2-ylsulfonyl)-N-methoxy-N-methylacetamide and α-chloro-ketone, starting reagent for the one-pot synthesis of 2-heptyl-3-hydroxyl-4(1H)-quinolone (PQS), signaling molecule in the quorum sensing of Pseudomonas aeruginosa.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2-8°C. Incompatible with oxidizing agents.

Literature References

Beedimane Narayana Manjunath.; Neeraj P. Sane andIndrapal Singh Aidhen. New Reagent for Convenient Access to the α,β-Unsaturated N-Methoxy-N-methyl-amide Functionality by a Synthesis Based on the Julia Olefination Protocol. European Journal of Organic Chemistry. 2006, 12 (2006), 2851-2855.

James T Hodgkinson.; Warren R J D Galloway.; Martin Welch.; David R Spring. Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs. Nature Protocols. 2012, 7 1184-1192.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1924015
Harmonized Tariff Code
2928.00
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware