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L17527 1-Boc-isonipecotic acid, 98+%

CAS Number
84358-13-4
Synonyms
Boc-DL-Inp-OH
1-(tert-Butoxycarbonyl)isonipecotic acid

Stock No. Size Price ($) Quantity Availability
L17527-03 1g 37.60
L17527-06 5g 130.00
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1-Boc-isonipecotic acid, 98+%

MDL
MFCD00076999

Chemical Properties

Formula
C11H19NO4
Formula Weight
229.28
Melting point
149-151°
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

It is a pharmaceutical intermediate. he camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

Notes

Store in cool dry conditions in well sealed containers. Incompatible with strong oxidizing agents.

Literature References

Vincent J. Venditto.; Kimberly Allred.; Clinton D. Allred.; Eric E. Simanek. Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.Chem. Commun. 2009, (37),5541-5542 .

Pavol Zlatoidsky.; Tibor Maliar. Synthesis and structure-activity relationship study of the new set of trypsin-like proteinase inhibitors. European Journal of Medicinal Chemistry. 1999, 34 (12),1023-1034 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2933.39
TSCA
No

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