Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

112275-50-0 - 1-Boc-homopiperazine, 98% - 1-(tert-Butoxycarbonyl)homopiperazine - tert-Butyl hexahydro-1,4-diazepine-1-carboxylate - L17728 - Alfa Aesar

L17728 1-Boc-homopiperazine, 98%

CAS Number
112275-50-0
Synonyms
1-(tert-Butoxycarbonyl)homopiperazine
tert-Butyl hexahydro-1,4-diazepine-1-carboxylate

Size Price ($) Quantity Availability
1g 40.60
5g 112.00
Add to Cart Add to Quote Request View Item

1-Boc-homopiperazine, 98%

MDL
MFCD00276987

Chemical Properties

Formula
C10H20N2O2
Formula Weight
200.28
Boiling Point
90°/0.5mm
Flash Point
>110°(230°F)
Density
1.016
Refractive Index
1.4710
Sensitivity
Air Sensitive
Solubility
Not miscible or difficult to mix in water.

Applications

1-Boc-homopiperazine is used in synthesis of potent anticoagulant. It is also used to produce 4-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester by reaction with 11-bromo-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. It is sensitive to air.

Literature References

Hiroyuki Koshio.; Fukushi Hirayama.; Tsukasa Ishihara.; Yuta Taniuchi.; Kazuo Sato.; Yumiko Sakai-Moritani.; Seiji Kaku.; Tomihisa Kawasaki.; Yuzo Matsumoto.; Shuichi Sakamoto.; Shin-ichi Tsukamoto. Synthesis and biological activity of novel 1,4-diazepane derivatives as factor Xa inhibitor with potent anticoagulant and antithrombotic activity. Bioorganic & Medicinal Chemistry. 2004, 12 (9), 2179-2191.

Saito, K.; Nakao, A.; Shinozuka, T.; Shimada, K.; Matsui, S.; Oizumi, K.; Naito, S. Discovery and structure-activity relationship of thienopyridine derivatives as bone anabolic agents. Bioorganic & medicinal chemistry. 2013, 21 (7), 1628-1642.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
7581789
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2933.99
TSCA
No

Recommended

  • A14657

    3-(Trifluoromethyl)benzenesulfonyl chloride, 98%
  • A15529

    4'-(Trifluoromethyl)acetophenone, 98+%
  • A18354

    4-n-Propylbenzenesulfonyl chloride, 95%
  • H52424

    (S)-1-Boc-2-isopropylpiperazine, 97%
  • H52738

    (S)-1-Boc-2-ethylpiperazine, 97%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware