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1172493-99-0 - 4-Sulfamidobenzoyl chloride DMF complex, 95% - 4-(Aminosulfonyl)benzoyl chloride - 4-(Chlorocarbonyl)benzenesulfonamide - L18428 - Alfa Aesar

L18428 4-Sulfamidobenzoyl chloride DMF complex, 95%

CAS Number
1172493-99-0
Synonyms
4-(Aminosulfonyl)benzoyl chloride
4-(Chlorocarbonyl)benzenesulfonamide

Size Price ($) Quantity Availability
1g 48.00
5g 156.56
25g 575.10
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4-Sulfamidobenzoyl chloride DMF complex, 95%

MDL
MFCD02094019

Chemical Properties

Formula
C10H13ClN2O4S
Formula Weight
292.74
Sensitivity
Moisture Sensitive
Solubility
Decomposes in water.

Applications

It was used in the discovery of 2-Phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors and in the synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors.

Notes

Moisture sensitive. Store away from water/moisture, strong bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Literature References

Wenhui Hu, et al. Discovery of 2-Phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors.Bioorg. Med. Chem.,2003,11(24), 5539-5544.

Wenhui Hu, et al. Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors.J. Am. Chem. Soc.,1997,119(11), 2614-2627.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2935.00
TSCA
No

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