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(R)-(+)-1-Octyn-3-ol is used as an intermediate for the synthesis of prostaglandins, modified eicosanoids structured with fatty acids attached to a 5 membered ring.
Kazuhiko Matsumura.; Shohei Hashiguchi.; Takao Ikariya.; Ryoji Noyori. Asymmetric Transfer Hydrogenation of α,?β-Acetylenic Ketones. J. Org. Chem. 1997, 119 (37), 8738-8739.
Thomas Schubert.; Werner Hummel.; Maria-Regina Kula.; Michael Müller. Enantioselective Synthesis of Both Enantiomers of Various Propargylic Alcohols by Use of Two Oxidoreductases. European Journal of Organic Chemistry. 2001, 2001 (22), 4181-4187.
Hazard Statements: H227-H315-H319-H335
Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant