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Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
HM Zonderland.; EG Coerkamp.; J Hermans. Diagnosis of Breast Cancer: Contribution of US as an Adjunct to Mammography 1. Radiology. 1999 213 (2), 255-300.
M Kriege.; C Brekelmans.; C Boetes.; SH Muller. Differences between first and subsequent rounds of the MRISC breast cancer screening program for women with a familial or genetic predisposition. Cancer. 2006 106 (11), 2318-2326.
Hazard Statements: H302+H312+H332-H319
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes serious eye irritation.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P337+P313-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant