(S)-(-)-1-Phenylethylamine is utilized in a one-pot, multi-component synthesis of a highly substituted, chiral pyrrole.
For use as a chiral auxiliary in the asymmetric synthesis of (R)-(-)-10-methyl-1(9)-octal-2-one, see: Org. Synth. Coll., 9, 610 (1998):
Cassimjee, K. E.; Humble, M. S.; Land, H.; Abedi, V.; Berglund, P. Chromobacterium violaceum ω-transaminase variant Trp60Cys shows increased specificity for (S)-1-phenylethylamine and 4'-substituted acetophenones, and follows Swain-Lupton parameterisation. Org. Biomol. Chem. 2012, 10 (28), 5466-5470.
Cui, S.; Wang, T.; Hu, X. Synthesis, characterization, and DFT studies of a new chiral ionic liquid from (S)-1-phenylethylamine. Spectrochim. Acta, Part A 2014, 133, 778-784.
Hazard Statements: H227-H302-H311-H314-H318
Combustible liquid. Harmful if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280a-P304+P340-P405-P501a
Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.