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374898-01-8 - (R)-(+)-1-(4-Fluorophenyl)ethylamine, ChiPros 99%, ee 98% - (R)-4-Fluoro-alpha-methylbenzylamine - L19120 - Alfa Aesar

L19120 (R)-(+)-1-(4-Fluorophenyl)ethylamine, ChiPros 99%, ee 98%

CAS Number
374898-01-8
Synonyms
(R)-4-Fluoro-alpha-methylbenzylamine

Size Price ($) Quantity Availability
1g 49.75
5g 99.20
25g 337.60
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(R)-(+)-1-(4-Fluorophenyl)ethylamine, ChiPros 99%, ee 98%

MDL
MFCD03093090

Chemical Properties

Formula
C8H10FN
Formula Weight
139.17
Melting point
-30°
Boiling Point
76°/22mm
Flash Point
68°(154°F)
Density
1.030
Refractive Index
1.5020
Sensitivity
Air Sensitive
Solubility
Sparingly Soluble in water (1.5E-3 g/L) (25°C).

Applications

(R)-(+)-1-(4-Fluorophenyl)ethylamine, is used as a pharmaceutical intermediate and as a chemical in organic synthesis

Notes

Air Sensitive. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.

Literature References

WK Hagmann. The many roles for fluorine in medicinal chemistry. Journal of medicinal chemistry. 2008 51 (15), 4359-4369.

BD Roth.; CJ Blankley.; AW Chucholowski. Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus. Journal of medicinal chemistry. 1991 34 (1), 357-366.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H227

Causes severe skin burns and eye damage. Combustible liquid.

Precautionary Statements: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
8614058
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2921.49
TSCA
No

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