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2-Methylimidazo[4,5-c]pyridine is used as a antagonist against platelet-activating factor (PAF).
M. Jonathan Fray, Kelvin Cooper, M. John Parry, Kenneth Richardson, John Steele. Novel Antagonists of Platelet-Activating Factor. 1. Synthesis and Structure-Activity Relationships of Benzodiazepine and Benzazepine Derivatives of 2-Methyl-1-phenylimidazo[4,5-c]pyridine. J. Med. Chem. 1995, 38 (18), 3514-3523.
M. Jonathan Fray, David J. Bull, Kelvin Cooper, M. John Parry, Mark H. Stefaniak. Novel Antagonists of Platelet-Activating Factor. 2. Synthesis and Structure-Activity Relationships of Potent and Long-Acting Heterofused [1,5]Benzodiazepine and [1,4]Diazepine Derivatives of 1-Phenyl-2-methylimidazo[4,5-c]pyridine. J. Med. Chem. 1995, 38 (18), 3524-3535.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.