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Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.
Mancebo-Aracil, J.; Nájera, C.; Sansano, J. M. Binap-silver-catalyzed enantioselective multicomponent 1,3-dipolar cycloaddition of azomethines ylides derived from ethyl glyoxylate. Tetrahedron: Asymmetry 2015, 26 (12-13), 674-678.
Barbier, V.; Couty, F.; David, O. R. P. Morita-Baylis-Hillman Reactions with Nitroalkenes: A Case Study. Eur. J. Org. Chem. 2015, 2015 (17), 3679-3688.
Hazard Statements: H225-H302-H333-H315-H361-H336-H373-H304
Highly flammable liquid and vapour. Harmful if swallowed. May be harmful if inhaled. Causes skin irritation. Suspected of damaging fertility or the unborn child. May cause drowsiness or dizziness. May cause damage to organs through prolonged or repeated exposure. May be fatal if swallowed and enters airways.
Precautionary Statements: P210-P260-P301+P310a-P303+P361+P353-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. IF SWALLOWED: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.