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459-04-1 - 4-Fluorophenylacetyl chloride, 97% - L19235 - Alfa Aesar

L19235 4-Fluorophenylacetyl chloride, 97%

CAS Number
459-04-1
Synonyms

Size Price ($) Quantity Availability
1g 42.00
5g 134.00
25g 467.00
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4-Fluorophenylacetyl chloride, 97%

MDL
MFCD00674181
EINECS
000-000-0

Chemical Properties

Formula
C8H6ClFO
Formula Weight
172.59
Boiling Point
60°/8mm
Flash Point
107°(224°F)
Density
1.259
Refractive Index
1.5120
Sensitivity
Moisture Sensitive
Solubility
Miscible with dichloromethane.

Applications

4-Fluorophenylacetyl chloride is used as an acylating agent in organic synthesis. It is used to prepare monoacylated pyrazolidine by reacting with pyrazolidine. It is also used in the preparation of N-acyl isothiouronium chloride.

Notes

Moisture Sensitive. Store in a cool place. Incompatible with water, alcohols, oxidizing agents and strong bases.

Literature References

Kalalbandi, V. K. A.; Seetharamappa, J.; Katrahalli, U. Synthesis, crystal studies and in vivo anti-hyperlipidemic activities of indole derivatives containing fluvastatin nucleus. RSC Adv. 2015, 5 (48), 38748-38759.

Garazd, M. M.; Garazd, Y. L.; Ogorodniichuk, A. S.; Khilya, V. P. Modified coumarins. 29. Synthesis of structural analogs of natural 6-arylfuro[3,2-g]chromen-7-ones. Chem. Nat. Compd. 2009, 45 (2), 158-163.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260u-P201-P280i-P304+P340-P405-P501a

Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
972148
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2916.39
TSCA
No

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