Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

15656-28-7 - Bis(pyridine)iodonium tetrafluoroborate, 97% - Barluenga's Reagent - L19385 - Alfa Aesar

L19385 Bis(pyridine)iodonium tetrafluoroborate, 97%

CAS Number
Barluenga's Reagent

Size Price ($) Quantity Availability
250mg 25.00
1g 60.20
Add to Cart Add to Quote Request View Item

Bis(pyridine)iodonium tetrafluoroborate, 97%


Chemical Properties

Formula Weight
Melting point
ca 160° dec.
Moisture & Light Sensitive
Hydrolyzes in water.


Bis(pyridine)iodonium tetrafluoroborate is used as mild iodinating and oxidizing reagent. It is also useful for selective iodination of free phenolic groups in tyrosine residues during solid-phase synthesis.


Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Yoshifumi Maegawa.; Yasutomo Goto.; Shinji Inagaki.; Toyoshi Shimada. A useful procedure for diiodination of carbazoles and subsequent efficient transformation to novel 3,6-bis(triethoxysilyl)carbazoles giving mesoporous materials. Tetrahedron Letters. 2006, 47 (39), 6957-6960.

Benito Alcaide.; Pedro Almendros.; Amparo Luna.; M. Rosario Torres. Divergent Reactivity of 2-Azetidinone-Tethered Allenols with Electrophilic Reagents: Controlled Ring Expansion versus Spirocyclization. Advanced Synthesis & Catalysis. 2010, 352 (4), 621-626.

Powerful electrophilic iodinating agent; reagent of choice for selective iodinations, under mild conditions, of alkenes: Angew. Chem. Int. Ed., 27, 1715 (1985), acetylenes: J. Org. Chem., 55, 3104 (1990), and aromatic compounds: J. Org. Chem., 58, 2058 (1993); Tetrahedron Lett., 34, 3893 (1993).

Useful for selective iodination of free phenolic groups in tyrosine residues during solid-phase synthesis: Tetrahedron Lett., 39, 7393 (1998); 40, 7279 (1999). Photolysis of cycloalkanols in the presence of cesium carbonate affords ring-opened ω -iodocarbonyl compounds in good yield: Angew. Chem. Int. Ed., 40, 3389 (2001).

Photochemical oxidations with the reagent have been reported, e.g. cleavage of 1,2-diols to aldehydes, and oxidation of alcohols to aldehydes or ketones: Chem. Eur. J., 10, 4206 (2004).

For a brief review on uses of the reagent in synthesis, see: Synlett, 1679 (1999).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code


  • A10173

    Trifluoromethanesulfonic acid, 98+%
  • A11009

    Benzaldehyde dimethyl acetal, 99%
  • A13163

    1,10-Phenanthroline, 99%, may contain up to 1.5% water
  • A15708

    Pyridinium p-toluenesulfonate, 98+%
  • 18208

    Tetrafluoroboric acid-diethyl ether complex, 50-55% w/w HBF4

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware