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(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.
A Naylor.; D B Judd.; D I Scopes.; A G Hayes.; P J Birch. 4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists. Journal of Medicinal Chemistry. 1994, 37 (14), 2138-2144.
Mitsunori Hashimoto.; Yutaka Eda.; Yasutomo Osanai.; Toshiaki Iwai.; Seiichi Aoki. A Novel Decarboxylation of α-amino acids. A Facile Method of Decarboxylation by the use of 2-Cyclohexen-1-one as a Catalyst. Chemistry Letters. 1986, 15 (6), 893-896.
Product of Toray Industries, Inc.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant