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86-59-9 - Quinoline-8-carboxylic acid, 98+% - L19644 - Alfa Aesar

L19644 Quinoline-8-carboxylic acid, 98+%

CAS Number
86-59-9
Synonyms

Size Price ($) Quantity Availability
250mg 53.90
1g 139.00
5g 546.00
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Quinoline-8-carboxylic acid, 98+%

MDL
MFCD00047619
EINECS
000-000-0

Chemical Properties

Formula
C10H7NO2
Formula Weight
173.17
Melting point
185-189°
Solubility
Soluble in water. (3.1 g/L)

Applications

8-Quinolinecarboxylic acid may be used in the synthesis of novel oxorhenium(V) complexes incorporating quinoline and isoquinoline carboxylic acid derivatives, chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline compounds, used as ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones and chiral quinolinyl-oxazoline compounds, used as ligands for Cu(II) catalyzed asymmetric cyclopropanation.

Notes

Store at room temperature. Incompatible with oxidizing agents.

Literature References

Faten Sliman.; Mélina Blairvacq.; Emilie Durieu.; Laurent Meijer.; Jordi Rodrigo.; Didier Desmaële. Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.Bioorg. Med. Chem. Lett. 2010, 20 (9),2801-2805 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8070
Beilstein
19176
Harmonized Tariff Code
2933.49
TSCA
No

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