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147081-44-5 - (S)-(-)-1-Boc-3-aminopyrrolidine, 98%, ee 99% - (S)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine - L19696 - Alfa Aesar

L19696 (S)-(-)-1-Boc-3-aminopyrrolidine, 98%, ee 99%

CAS Number
147081-44-5
Synonyms
(S)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine

Size Price ($) Quantity Availability
1g 93.60
5g 303.00
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(S)-(-)-1-Boc-3-aminopyrrolidine, 98%, ee 99%

MDL
MFCD03419271

Chemical Properties

Formula
C9H18N2O2
Formula Weight
186.25
Boiling Point
115°/4mm
Density
1.020
Refractive Index
1.4715
Sensitivity
Air Sensitive

Applications

(S)-(-)-1-Boc-3-aminopyrrolidine is specifically used to protect amine in the solid phase synthesis of peptides. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

Notes

Store under inert gas. It is sensitive to air. Store in a cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Jiwon Seo.; Pavel Martásek.; Linda J. Romanb.; Richard B. Silverman. Selective l-nitroargininylaminopyrrolidine and l-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors. Bioorganic & Medicinal Chemistry. 2007, 15 (5), 1928-1938.

Takaaki Sumiyoshi.; Takeshi Enomoto.; Kentaro Takai.; Yoko Takahashi.; Yasuko Konishi.; Yoshiharu Uruno.; Kengo Tojo.; Atsushi Suwa.; Harumi Matsuda.; Tomokazu Nakako.; Mutsuko Sakai.; Atsushi Kitamura.; Yasuaki Uematsu.; Akihiko Kiyoshi. Discovery of Novel N-Substituted Oxindoles as Selective M1 and M4 Muscarinic Acetylcholine Receptors Partial Agonists. ACS Med. Chem. Lett. 2013, 4 (2), 244-248.

Product of Toray Industries, Inc.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P305+P351+P338-P309-P310a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell:

Other References

Beilstein
8312125
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2933.99
TSCA
No

Recommended

  • H28188

    (R)-(+)-1-Boc-3-aminopyrrolidine, 97%
  • H52819

    4-Aminomethyl-1-Boc-piperidine, 97%

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