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4-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that has been used to study the regulation of that enzyme.
R.Shiman; D.W.Gray; M.A.Hill. Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site. Journal of Biological Chemistry. 1994, 269,(40), 24637-24646.
P.J.Hillas; P.F.Fitzpatrick. A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines. Biochemistry (Washington). 1996, 35,(22), 6969-6975.