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4-Chloropyridine-3-carboxylic acid is a building block used in a synthesis of benzocanthinones via tributyltin hydride radical induced cyclization. 4-Chloropyridine-3-carboxylic acid is also used in a synthesis of heterocyclic analogues of xanthone.
Edward C. Taylor.; John S. Driscoll. Pyridine-1-oxides. V. 4-Substituted Nicotinic Acid-1-oxides1. J. Am. Chem. Soc. 1960, 82, (12), 3141-3143.
Edward C. Taylor.; Wendell A. Ehrhart. A Convenient Synthesis of Formamidine and Acetamidine Acetate. J. Am. Chem. Soc. 1960, 82, (12), 3138-3141.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.