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It has been used in the studies on some heterocyclic ligands showing linked ionization effects. 4-(Hydroxymethyl)imidazole HCl has been used in the synthesis of imidazole-containing peptidomimetic inhibitors.
Roslyn Atkins, et al. Copper(II) and nickel(II) complexes of unsymmetrical tetradentate Schiff base ligands.Inorg. Chem.,1985,24(2), 127-134.
Jukka Mäki. Bi-imidazole nucleosides obtained by ring opening of etheno and substituted etheno derivatives of adenosine.J. Chem. Soc., Perkin Trans. 1,2000,(24), 4445-4450.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.