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Dioxanes (dioxacyclohexanes), are six membered cyclic organic compounds containing two oxygen atoms. Depending on the relative positions of oxygen atoms three isomers are possible - 1,2-dioxane, 1,3-dioxane and 1,4-dioxane. Most of the dioxanes are 1,4-isomers. Simple 1,4-dioxane is a versatile aprotic solvent used for a variety of practical applications. It has higher boiling range and less toxicity compared to tetrahydrofuran and hence used as a substitute to THF in some chemical processes. Owing to its oxygen atoms, they act as a Lewis base and are used to solvate many inorganic compounds. Dioxane finds use as a stabilizer for 1,1,1-trichloroethane for storage in aluminium containers by forming an adduct with aluminium chloride, and as a solvent in inks and adhesives. A dioxane solution of sulfur trioxide is useful for Beckmann rearrangements, sulfonation of alkenes, and arenes. Dioxane based compounds find use as chiral solvating agents for the determination of enantiomeric excess and as chiral derivatizing agents in the determination of absolute configuration. 1,3-Dioxanes are employed as a means of protection of carbonyl groups during organic transformations.