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These solvents are made specifically for a HPLC instrument. HPLC grade solvents are prepared by a distillation process to remove the volatile impurities followed by filtration to achieve high purity solvents. These impurities if found will contaminate the column and reduce the lifetime.
These solvents are generally produced with maximum purity and also free of particles up to 0.02 micron. These solvents have low UV-absorption and low peak interference.
HPLC grade solvents are used to reduce the detector noise, baseline drifts, and to enhance the quality of data. Analytical column life time will be extended by usage of high pure HPLC solvents. The usage of HPLC solvents in quality control laboratories will help assure reproducibility.