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Nucleosides and nucleotides are the building blocks of RNA and DNA. They are derived from nitrogenous bases and are either purines (adenine and guanine) or pyrimidines (cytosine, uracil, and thymine). Nucleosides are glycosylamines consisting of a purine or pyrimidine base covalently linked to a ribose or deoxyribose sugar. Nucleotides are the 5'-phosphate esters of nucleosides and may contain one to three phosphate groups. Nucleosides and nucleotides, when assembled to RNA and DNA, are responsible for encoding, transmitting and expressing genetic information in all organisms.
Several nucleoside analogues are to inhibit DNA and RNA replication in viruses or oncogenic cells. Nucleic acid analogues are also used to study enzyme inhibition and for sequencing analyses. Alfa AesarÆs supplies a range of high quality nucleosides and nucleotides and also their derivatives and analogues.