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Organo fluorines (also known as Organic fluoro compounds) are organic compounds, which contain a carbon-fluorine bond. Fluorine has the highest electronegativity of all elements (3.98), which causes the high dipole moment of the C-F bond. In general, fluorocarbons with single bonds are stable, whereas unsaturated fluorocarbons are more reactive. Fluorocarbons are chemically and thermally more stable than hydrocarbons. Organo fluorine reagents such as triflic acid (CF3SO3H) and trifluoroacetic acid (CF3CO2H) are useful throughout organic synthesis. Fluorocarbon anions (for example, (C6F5)4-) are employed in the Ziegler-Natta catalysis reaction.

Organo fluorine compounds are commonly used in a vast range of applications including: agrochemicals, fluoropolymers, refrigerants, surfactants, anesthetics, oil-repellents, catalysis, and water-repellents. In the pharmaceutical field, many of the approved drugs are organo fluorine compounds (e.g. fluoroquinolones for bacterial infections). Some of the difluoro derivatives are reported as biologically active compounds. Additionally, perfluorinated alkanes are used as blood substitutes. In the chemical industry, organo fluorine compounds are also used as solvents (dichlorodifluoromethane), as surfactants (polyfluorinated derivatives), and as ligands in coordination chemistry.

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