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Reactions Involving Carbonyl Compounds

reactions involving carbonyl compounds   Named Reactions in Organic Synthesis

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A carbonyl group is a functional group consisting of a carbon atom joined to an oxygen atom by a double bond. The carbonyl group is present in many of the most synthetically important functional groups, including those of aldehydes, ketones, esters, amides and other carboxylic acid derivatives. Indeed, the majority of reactions involving these chemistries directly involve the carbonyl group. Consequently, the carbonyl group plays a key role in a wide range of synthetically important chemical reactions and biological processes.

One of the earliest named reactions involving carbonyl group chemistry is the Aldol reaction, which involves the addition of the enol/enolate of a carbonyl compound to an aldehyde or ketone.

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Other well-known named reactions that feature carbonyl groups include: Barbier coupling reaction, Baylis–Hillman reaction, Corey–Chaykovsky epoxidation, Corey–Fuchs alkyne synthesis, Dakin oxidation, Eschweiler–Clarke methylation, Evans aldol reaction, Hantzsch dihydropyridine synthesis, Pictet–Spengler tetrahydroisoquinoline synthesis, and Stetter reaction

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Electrophilic aromatic substitution

Nucleophilic substitution reactions

Heterocycle-formation

Transition metal-catalyzed couplings

Oxidation

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