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During protein expression proteases can begin degrading proteins of interest as soon as cells and tissues are lysed. In order to preserve the activity and nature of proteins of interest, lysates are often treated with a mixture of protease inhibitors. Alfa Aesar offers a number of protease inhibitors to prevent protein sample degradation by the most common proteases. We also offer protease and phosphatase inhibitor cocktails to prevent lysis from multiple enzymes at once. These products are widely used in protein analytical research to protect proteins from proteolytic degradation.

  • 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
  • 3,4-Dichloroisocoumarin, 98%
  • 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%
  • 4',5,7-Trihydroxyisoflavone, 99+%
  • alpha-Toluenesulfonyl fluoride, 99%
  • AM 580
  • Antipain dihydrochloride
  • Aprotinin, from bovine lung
  • Aprotinin, from bovine lung, Thermo Scientific
  • Bestatin
  • Bestatin hydrochloride, 98%
  • Calpain Inhibitor XI
  • Calpain Inhibitor XII
  • Calpeptin, 98+%
  • Camostat methanesulfate, 98%
  • DAPT
  • E-64
  • Elastase Inhibitor II
  • Elastase Inhibitor III
    Elastase inhibitor III, or MeOSuc-Ala-Ala-Pro-Val chloromethyl ketone, inhibits human leukocyte elastase (HLE). It is cell permeable and because of the chloromethyl ketone group, it irreversibly inhibits the enzyme. HLE is a serine protease found in the azurophilic granules of polymorphononuclear leukocytes. When then enzyme is released from the cell it can hydrolyze elastin and collagen. Increased HLE activity has been is associated with several diseases including rheumatoid arthritis and cystic fibrosis.
  • Elastatinal
  • gamma-Secretase Inhibitor II
  • Genistin, 99+%
  • GM 6001
  • GM 6001, Negative Control
  • GW 9662
  • Nalpha-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, 98%
  • N-Fmoc-Tyr-Ala diazomethyl ketone
  • N-Methoxysuccinyl-Phe-Leu-Phe-7-amino-4-(trifluoromethyl)coumarin
  • Okadaic acid, 98%
  • Okadaic acid potassium salt, 98%
  • Okadaic acid sodium salt, 98%
  • Omi/HtrA2 Protease Inhibitor
  • Pepstatin A, 98%
  • Pepstatin A, Thermo Scientific
  • Phosphatase Inhibitor Cocktail A
  • Phosphatase Inhibitor Cocktail I
  • Phosphatase Inhibitor Cocktail II
  • Phosphatase Inhibitor Cocktail III
  • Phosphatase Inhibitor Cocktail IV
  • Prolyl Endopeptidase Inhibitor
  • Protease Inhibitor Cocktail, for general use
  • Protease Inhibitor Cocktail, for mammalian cells
  • Protease Inhibitor Cocktail I
  • Protease Inhibitor Cocktail I, Animal Free
  • Protease Inhibitor Cocktail II
  • Protease Inhibitor Cocktail III
  • Protease Inhibitor Cocktail III, Animal-Free
  • Protease Inhibitor Cocktail III, Animal-Free, DMSO-Free
  • Protease Inhibitor Cocktail IV
  • Protease Inhibitor Cocktail V, EDTA-Free, Animal-Free


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