Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

623-00-7 - 4-Bromobenzonitrile, 98+% - 4-Cyanobromobenzene - A10914 - Alfa Aesar

A10914 4-Bromobenzonitrile, 98+%

Número CAS
623-00-7
Nombre Alternativo
4-Cyanobromobenzene

Tamaño Precio ($) Cantidad Disponibilidad
10g 39,40
50g 147,00
250g 548,00
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

4-Bromobenzonitrile, 98+%

MDL
MFCD00001811
EINECS
210-764-9

Propiedades químicas

Fórmula
C7H4BrN
Peso molecular
182.03
Punto de fusión
111-114°
Punto de ebullición
235-237°
Punto de inflamabilidad
130°(266°F)
Densidad
1.562
Solubilidad
Very slightly soluble in water(0.2g/L). Soluble in alcohol and ether.

Aplicaciones

4-Bromobenzonitrile is used as reagents and solvents. Reaction of 2-propanol, 4-bromobenzonitrile, and NaH in the presence of 1.5 mol % Pd2(dba)3 and 3 mol % (S)-(-)2,2?-bis(di-p-tolylphosphino)- 1,1?-binaphthyl at 50°C afforded 4-isopropoxy- benzonitrile in 80% isolated yield. The synthesis of 4-cyanobiphenyl at room temperature in a flow injection microreactor, using a supported catalyst, without the addition of a base gave a product yield of 67±7% (n=6). This was achieved by injecting 4-bromobenzonitrile. The 3-arylation of 2,5-dimethylthiophene with 4-bromopropiophenone, 4-trifluoromethylbromobenzene or 4-bromobenzonitrile gave 3-5 in only 38-50% yields in Palladium-catalysed direct 3-or 4-arylation of thiophene derivatives using aryl bromides.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Referencias documentales

Michael Palucki,; John P. Wolf,; Stephen L. Buchwald. Palladium-Catalyzed Intermolecular Carbon-Oxygen Bond Formation:? A New Synthesis of Aryl Ethers. J. Am. Chem. Soc. 1997, 119 (14), 3395-3396.

Gillian M Greenway,; Stephen J Haswell,; David O Morgan,; Victoria Skelton,; Peter Styring. The use of a novel microreactor for high throughput continuous flow organic synthesis. Sensors and Actuators B: Chemical. 2000, (3) ,153-158.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H301-H312-H331-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
2041518
Clase de peligro
6.1
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2926.90
TSCA
No
RTECS
DI2460000

Recomendado

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio