Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

110-86-1 - Pyridine, 99+% - A12005 - Alfa Aesar

A12005 Pyridine, 99+%

Número CAS
110-86-1
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
500ml 35,79
2500ml 113,30
10000ml 408,91
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

Pyridine, 99+%

MDL
MFCD00011732
EINECS
203-809-9

Propiedades químicas

Fórmula
C5H5N
Peso molecular
79.10
Punto de fusión
-42°
Punto de ebullición
115°
Punto de inflamabilidad
20°(68°F)
Densidad
0.978
Índice de refracción
1.5100
Solubilidad
Miscible with water, alcohol, ether, pet ether, and oils.

Aplicaciones

As polar, basic, low-reactive solvent, precursor, and reagent, pyridine finds wide range of applications in pharmaceuticals, agrochemicals and in the manufacture of dyes and rubber. Further it is used in the textile industry to improve network capacity of cotton. Pyridine finds applications in specialty chemical reagents like Cornforth reagent (pyridinium dichromate, PDC), pyridinium chlorochromate (PCC), the Collins reagent (complex of chromium(VI) oxide with pyridine) and the Sarret reagent (complex of chromium(VI) oxide with pyridine). Pyridine is a widely used ligand in coordination chemistry. Pyridine-base adducts like pyridine-borane and pyridine-sulfur trioxide are widely used owing to their superior characteristics in their reactivity and solubility characteristics.

Notas

Pyridine is stable under normal temperatures and pressures. It is incompatible with strong oxidizing agents, and acids.

Referencias documentales

Baumann, M.; Baxendale I. R. An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles. Beilstein J. Org. Chem. 2013, 9, 2265-2319.

Bull, J. A.; Mousseau, J. J.; Pelletier, G.; Charette, A. B. Synthesis of pyridine and dihydropyridine derivatives by regio- and stereoselective addition to N-activated pyridines. Chem. Rev. 2012, 112 (5), 2642-2713.

Widely used as a base and nucleophilic catalyst in acylations, sulfonylations, etc. See also 4-(Dimethyl­amino)­pyridine, A13016.

Reacts with thionyl chloride to give N-(4-pyridyl)pyridinium chloride hydrochloride, a useful intermediate for the preparation of 4-substituted pyridines by nucleophilic displacement. Thus, reaction with sulfite ion gives the sulfonate: Org. Synth. Coll., 5, 977 (1973). Similarly, pyridine can be activated to substitution at the 4-position by reaction with Ethyl­ chloroformate, L06311, or tert-Butyl­dimethyl­silyl­ trifluoromethanesulfonate, A12174. The acyl or silyl pyridinium salt then reacts with Grignards or organocuprates, to give 4-substituted dihydropyridines which can readily be rearomatized: Bull. Chem. Soc. Jpn., 57, 1994 (1984).

For use in Cr(VI) oxidation reactions, see Chromium(VI)­ oxide, 12522.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H225-H302-H312-H332

Highly flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Indicaciones de precaución: P210-P261-P280-P240-P241-P303+P361+P353-P304+P340-P301+P312-P312-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,7970
Beilstein
103233
Clase de peligro
3
Grupo de embalaje
II
Código de tarifa arancelaria unificado
2933.31
TSCA
Yes
RTECS
UR8400000

Recomendado

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio