Lithiation with LDA occurs selectively on the side-chain. In a competitive study, the 2,3-dimethyl isomer was found to be attacked faster than the 2,6-isomer: J. Org. Chem., 48, 2130 (1983)./n
Indicaciones de peligro (UE): H226-H302-H315-H319-H335
Flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Indicaciones de precaución: P280h-P305+P351+P338
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.