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495-69-2 - Hippuric acid, 98% - N-Benzoylglycine - A12690 - Alfa Aesar

A12690 Hippuric acid, 98%

Número CAS
495-69-2
Nombre Alternativo
N-Benzoylglycine

Tamaño Precio ($) Cantidad Disponibilidad
100g 24,82
500g 73,23
1000g 134,93
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Hippuric acid, 98%

MDL
MFCD00002692
EINECS
207-806-3

Propiedades químicas

Fórmula
C9H9NO3
Peso molecular
179.18
Punto de fusión
188-191°
Densidad
1.371
Solubilidad
Soluble in water.

Aplicaciones

Hippuric acid is used as a intermediate for the manufacturing medicine and other organic compounds. Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins.

Notas

Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent.

Referencias documentales

A. N. Phippsa; J. Stewart; B. Wright; I. D. Wilson. Effect Of Diet On The Urinary Excretion Of Hippuric Acid And Other Dietary-Derived Aromatics In Rat. A Complex Interaction Between Diet, Gut Microflora And Substrate Specificity. Xenobiotica: The Fate Of Foreign Compounds In Biological Systems. 1998, 28(5), 527-537.

Quick, Aemand J. Ph.D., M.D.; Cooper, Mary A. B.S. The Synthesis Of Hippuric Acid: A New Test Of Liver Function. American Journal Of The Medical Sciences. 1933, 185(5), 630-635.

Condensation with aldehydes gives azlactones, which are intermediates in a classical route to amino acids; see, e.g.: Org. Synth. Coll., 2, 489 (1943). An alternative approach involves alkylation of the trianion of hippuric acid, prepared by LDA/TMEDA in THF: Tetrahedron Lett., 2205 (1976).

For cyclization with acetic anhydride to 2-phenyl-5-oxazolone, see: Org. Synth. Coll., 5, 946 (1973).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,4716
Beilstein
1073987
Código de tarifa arancelaria unificado
2924.29
TSCA
Yes
RTECS
MR8150000

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