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673-22-3 - 2-Hydroxy-4-methoxybenzaldehyde, 98% - 2-Hydroxy-p-anisaldehyde - 4-Methoxysalicylaldehyde - A12971 - Alfa Aesar

A12971 2-Hydroxy-4-methoxybenzaldehyde, 98%

Número CAS
673-22-3
Nombre Alternativo
2-Hydroxy-p-anisaldehyde
4-Methoxysalicylaldehyde

Tamaño Precio ($) Cantidad Disponibilidad
1g 18,70
5g 56,20
25g 180,00
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2-Hydroxy-4-methoxybenzaldehyde, 98%

MDL
MFCD00003327
EINECS
211-604-0

Propiedades químicas

Fórmula
C8H8O3
Peso molecular
152.15
Punto de fusión
40-44°
Punto de inflamabilidad
>110°(230°F)
Sensibilidad
Air Sensitive
Solubilidad
Solubility in methanol is almost transparent. Insoluble in water.

Aplicaciones

It is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.

Notas

Air sensitive. Store away from oxidizing agents, bases and air/oxygen. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Referencias documentales

Basak S, et al. Synthesis, crystal structures and fluorescence properties of two new di-and polynuclear Cd (II) complexes with N2O donor set of a tridentate Schiff base ligand.Polyhedron.,2008,27(4), 1193-1200.

Jihua Wang, et al. Antimicrobial and antioxidant activities of the root bark essential oil of Periploca sepium and its main component 2-hydroxy-4-methoxybenzaldehyde.Molecules.,2010,15(8), 5807-5817 .

I Kubo and I Kinst-Hori. 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants.lanta Med.,1999,65(1), 19-22.

Condensation with t-butyl acrylate results in cyclization to t-butyl 7-methoxychromene-3-carboxylate: J. Med. Chem., 36, 3580 (1993):

With (Ethoxycarbonyl­methyl­ene)­triphenyl­phosphorane, A12896, in N,N-diethylaniline cyclization to 7-methoxycoumarin occurs: Heterocycles, 39, 613 (1994).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P260-P201-P280g-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
1072443
Código de tarifa arancelaria unificado
2912.49
TSCA
Yes
RTECS
BZ2810000

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