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90-64-2 - (±)-Mandelic acid, 99% - (±)-alpha-Hydroxyphenylacetic acid - A14223 - Alfa Aesar

A14223 (±)-Mandelic acid, 99%

Número CAS
90-64-2
Nombre Alternativo
(±)-alpha-Hydroxyphenylacetic acid

(±)-Mandelic acid, 99%

MDL
MFCD00064250
EINECS
202-007-6

Propiedades químicas

Fórmula
C8H8O3
Peso molecular
152.15
Punto de fusión
118-121°
Sensibilidad
Light Sensitive
Solubilidad
Soluble in water, diethyl ether, ethanol and isopropanol.

Aplicaciones

Mandelic acid is used in the pharmaceutical industry as an antibacterial to treat urinary tract infections. It acts as a precursor for making various drugs. It is also used as an oral antibiotic. Mandelic acid peels are widely used for treating damaged skin due to its less penetrating and irritating property. Enantiomeric resolution of (±)-Mandelic acid is performed by using the chiral amine (1R,2S)-(-)-ephedrine followed by acidification to prepare (R)-( -)-Mandelic acid.

Notas

Hydrophobic and light sensitive. Incompatible with strong oxidizing agents and reducing agents.

Referencias documentales

Forms a cyclic isopropylidene derivative with acetone, providing a means of O-protection. Subsequent reaction with ammonia gives the amide: Org. Synth. Coll., 3, 536 (1955).

Langermann, J. V.; Temmel, E.; Morgenstern, A. S.; Lorenz, H. Solid Phase Behavior in the Chiral Systems of Various 2-Hydroxy-2-phenylacetic Acid (Mandelic Acid) Derivatives. J. Chem. Eng. 2015, 60 (3), 721-728.

Wang, X.; Cui, Y.; Xia, C.; Zhu, H.; Zhu, W.; Li, Y. Mandelic acid chiral separation utilizing a two-phase partitioning bioreactor built by polysulfone microspheres and immobilized enzymes. Bioprocess. Biosyst. Eng. 2015, 38 (3), 429-435.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H318

Causes serious eye damage.

Indicaciones de precaución: P280-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Otras referencias

Merck
14,5717
Beilstein
510011
Código de tarifa arancelaria unificado
2918.19
TSCA
Yes
RTECS
OO6300000

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